This study showed a high rate (38%) of standing test positivity in patients with long COVID. The ST-positive long COVID patients under 20 years of age had decreased circulating growth hormone levels.
Acute COVID-19, Long COVID, Post COVID-vaccination syndrome & Cardiovascular System-Clinical Studies
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Spontaneous dissection of the internal carotid artery in a fully vaccinated woman infected with SARS-CoV-2 (case report)
This case report describes a fully vaccinated woman positive for a non-Omicron variant of SARS-CoV-2 who experienced a spontaneous internal carotid dissection. A dissection was treated successfully with a flow-diverter stent.
Endothelial dysfunction detected after the second BNT162b2 mRNA COVID-19 vaccination was restored within six months
After the second BNT162b2 mRNA vaccination, brachial artery flow-mediated dilation assessment showed endothelial dysfunction in relatively healthy participants, which was restored within six months.
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Severe thickening and fibrosis of the vessel walls, smooth muscle cell proliferation, and lumen occlusion were found in the placental arteries of women infected with SARS-CoV-2
The results show severe vascular remodeling of placental arteries, including severe thickening of the vessel walls and the occlusion of the vessel lumen, in women with COVID-19 during pregnancy.
Higher 18F-FDG uptake was detected in the myocardium, axilla, liver, and spleen of asymptomatic vaccinated individuals up to 6 months after the second mRNA COVID-19 vaccination (PET/CT study)
Individuals who were asymptomatic and underwent PET/CT within a period of 180 days following their second vaccination had increased 18Fluorine-fluorodeoxyglucose uptake in the myocardium, axilla, liver, and spleen as compared to unvaccinated individuals.
SARS-CoV-2 can infect and replicate in macrophages within atherosclerotic plaques in the human coronary artery wall
SARS-CoV-2 was detected and replicated in the coronary arteries sampled at autopsy of severe COVID-19 cases. The virus targeted plaque macrophages and demonstrated a stronger tropism for arterial wall lesions than for perivascular fat.
The VAERS reporting rates of myocarditis/pericarditis after mRNA COVID-19 vaccination demonstrate a higher reporting rate mainly after the second dose, particularly among young males
In this retrospective pharmacovigilance study of safety signals associated with myocarditis/pericarditis after the primary and up to three booster doses of mRNA COVID-19 vaccines, the second dose of the vaccines showed the strongest signal in vaccinated individuals under 25 years old.
Cardiac MRI revealed signs of non-ischemic myocardial fibrosis in 30% of patients with long COVIDÂ syndrome
Non-ischemic, possibly post-inflammatory fibrosis, was found in 30% of patients with long COVID, exceeding the prevalence of this disease in the normal adult population.
Extensive thrombosis of cerebral venous sinuses and similar organization of cerebral thrombi were found in all three patients who died of vaccine-induced immune thrombotic thrombocytopenia
The authors performed the immunohistological analysis of clots from three people who died from cerebral venous thrombosis (CVT) related to vaccine-induced immune thrombotic thrombocytopenia (VITT)Â after receiving a single dose of ChAdOX1-nCoV-19, AstraZeneca/Oxford vaccines.
PET and MRI detected myocardial inflammation and edema in a small proportion of patients diagnosed with acute myocarditis within 14 days of mRNA COVID-19 vaccination
PET and MRI visualization of myocardial tissue has shown localized myocardial inflammation and edema in a small proportion of patients with symptomatic myocarditis approximately two months after COVID-19 vaccination.Â
The mRNA COVID-19 vaccination increases the risk of retinal vascular occlusion
The overall risk of all forms of retinal vascular occlusion was 2.19 times higher in the vaccinated cohort than in the unvaccinated cohort within two years after COVID-19 vaccination.
Patients with acute COVID-19 and convalescents who recovered after severe COVID-19 were found to have elevated levels of anti-desmoglein 2 autoantibodies
The results showed the possible association between anti-Dsg2 autoantibodies and post-COVID-19 cardiac sequelae.Â
