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Hospitalized patients with COVID-19 were found to have higher TMPRSS-2 and P450 aromatase levels and lower testosterone levels, suggesting that TMPRSS2, testosterone, and P450 aromatase can be used as markers of poor prognosis or increased disease severity in COVID-19.
Analysis of temporal antigen profiles, performed by collecting blood samples at multiple time points, revealed that the prevalence of SARS-CoV-2 plasma antigens was 10.6% 3-6 months after the onset of COVID-19, 8.7% after 6-10 months and 5.4% after 10-14 months.
This study showed the persistence of SARS-CoV-2 nucleic acid in solid tissue samples from various organs, including lung, liver, kidney, stomach, intestine, brain, breast, thyroid, blood vessels, and skin, in patients who had recovered from mild COVID-19 at one month, two months, and four months post-infection.
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This study described a case series of 28 patients who experienced de novo onset or flares of psoriasis following infection with the SARS-CoV-2 or vaccination. All of these patients were successfully managed with anti-IL-17 or anti-IL-23 medications.
These case reports presented individuals who were diagnosed with COVID-19 and who developed tuberculous pericarditis with tamponade.
This study investigated the presence of residual SARS-CoV-2 RNA and antigens in tissues of two patients diagnosed with post-COVID syndrome.Â
The results showed that different biological processes recovered in different time modes within two years after COVID-19, providing insights into the biological processes of the different long COVID syndrome phenotypes.
50% of subjects who received mRNA-based vaccines had specific fragments of recombinant S protein in their blood samples 2–6 months after vaccination.
HERV-W ENV protein was expressed in 58% of plasma samples of post-COVID patients, long after the acute SARS-CoV-2 infection was resolved .75% of post-COVID patients had elevated levels of anti-S and anti-N IgE antibodies compared to pre-pandemic controls.
This study investigated leprosy or immune-mediated complications known as leprosy reactions diagnosed in the Leprosy Clinic at the Hospital for Tropical Diseases, London, within 12 weeks following COVID-19 vaccination.
SARS-CoV-2 can induce the expression of the HERV-W envelope proteins, suggesting their involvement in COVID-19-associated pathology.
The largest case series of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) associated with SARS-CoV-2 infection and COVID-19 vaccination.
A lower 129Xe MRI RBC-to-barrier ratio in long COVID patients suggests that SARS-CoV-2 infection may have caused some microstructural abnormality to one or two volumes, such as pulmonary embolism, pulmonary blood flow alterations, or alveolar membrane thickening, which leads to decreased blood volume.
