The carbohydrate PL-M can reduce the viral load in Vero cells. In clinical studies with COVID-19 patients, PL-M treatment resulted in a rapid reduction of viral load and increased viral clearance, with no adverse effects.
COVID-19/ Post-COVID & Treatment
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Dose-dependent antiviral effect of probenecid in COVID-19
This study showed a dose-dependent antiviral effect of a uricosuric agent probenecid in patients with symptomatic, mild-to-moderate COVID-19.
Positive effects of the flavonol quercetin in COVID-19 or post-COVID-19 syndrome
Numerous studies demonstrated the positive effects of quercetin in in COVID-19 or post-COVID-19 syndrome, including direct inhibition of viral entry into the host cells, inhibition of viral replication, anti-inflammatory, antioxidant, immunomodulatory and neuroprotective effects.Â
Other Entries
Anti-SARS-CoV-2 properties of natural products derived from plants, honey, and marine sponges
This study analyzes recent research on natural products derived from plants, honey, and marine sponges with properties against the SARS-CoV-2, as well as several potential mechanisms of their action,
Metformin reduces the viral load of SARS-CoV-2 and the incidence of long COVID syndrome
Two randomized, placebo-controlled trials show that metformin reduces the viral load of SARS-CoV-2 and the incidence of long COVID syndrome.
Graded exercise therapy for individuals with long COVID syndrome and postexertional malaise: Pro et Contra
In their recent articles, several authors have discussed the clinical management of autonomic dysfunction and graded exercise therapy for individuals diagnosed with long-COVID or PACSÂ syndrome.
A virologic rebound and a substantially prolongated shedding of replication-competent viruses were found in 21% of vaccinated COVID-19 outpatients treated with nirmatrelvir-ritonavir
Virologic rebound in C-19 treated with nirmatrelvir–ritonavir, associated with the shedding of replication-competent viruses.
Acyclovir clinically resolved or significantly improved symptoms in patients diagnosed with long COVID syndrome
Two case series studies demonstrated that four patients with long COVID improved with chronic use of acyclovir.