Diffusion tensor imaging parameters were used to investigate microstructural abnormalities of brain tissue in individuals diagnosed with ME/CFS
Neuroscience-Clinical Studies
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Anti-GABAA receptor encephalitis developed after double autologous hematopoietic stem-cell transplantation for multiple myeloma (case report)
This case report presented a patient who developed autoimmune anti-GABAA receptor encephalitis after double autologous hematopoietic stem-cell transplantation for multiple myeloma.
Chronic traumatic encephalopathy (CTE) was found in 41% of brain samples of young athletes who died before 30 years of age
41% of of deceased young athletes who played contact sports and were exposed to repeated head impacts had chronic traumatic encephalopathy.
Other Entries
Intrathecally synthesized IgG1/CXCL10 axis is a potential predictor of multiple sclerosis activity
A specific signaling axis, immunoglobulin (Ig)G1-CXC motif chemokine ligand 10 (CXCL10), is a potential predictor of MS disease activity and/or conversion from clinically isolated syndrome to relapsing-remitting MS.
Neuroplasticity of the maternal brain during pregnancy and postpartum
The specific changes in physiology and neuroplasticity in the maternal brain during pregnancy prepare the mother for the challenges of motherhood and contribute to the survival of the offspring.
HERV expression in pregnant women with multiple sclerosis is reduced compared to healthy pregnant women
The expression of HERVs in pregnant women with MS was reduced compared to healthy pregnant women.
Structural brain changes in adolescents who had experienced childhood sexual abuse
This MRI study has shown that volumes of the amygdala and hippocampus, as well as the cortical thickness of the prefrontal cortex, were altered in sexually abused adolescents compared to non-abused adolescents.
Functional outcomes in patients with locked-in syndrome (Norwegian National Study)
The majority of patients with locked-in syndrome remain severely disabled, but, even small improvements in function can significantly increase the potential for activity and participation.
Semorinemab, an anti-tau monoclonal antibody, did not improve functional and global outcomes in patients with mild-to-moderate Alzheimer’s disease (the phase II Lauriet study)
Results showed that semorinemab had a modest positive cognitive effect in patients with mild to moderate AD, but, did not result in improved functional or global outcomes.
IL-6 receptor blocker-tocilizumab rapidly improved condition in two children with severe myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD)
IL-6 receptor blocker tocilizumab rapidly improved the condition in two children with severe, acute manifestations of myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD).
Metabolomic analysis revealed three metabolites as candidates for “toxic” gut-brain communication in patients with multiple sclerosis
Three metabolites from catabolism of two essential amino acids, tryptophan and phenylalanine, represent possible candidates for ‘toxic’ gut–brain communication in patients with multiple sclerosis.
An unusual outbreak of Guillain Barré Syndrome in Peru
The Pan American Health Organization as the regional office for the World Health Organization in the Americas issued a briefing note on July 10, 2023, regarding the unusual increase of cases of Guillain Barré Syndrome in different parts of Peru.
Healthy older people treated with daily low-dose aspirin had higher rates of intracranial hemorrhage compared to the placebo group (the ASPREE randomized clinical trial)
The totals of intracranial hemorrhage resulting from a combination of hemorrhagic stroke and other causes of intracerebral hemorrhage, such as subdural, extradural, and subarachnoid bleeding, were significantly higher among individuals treated with aspirin than in individuals assigned to placebo.
Recurrent aseptic meningitis associated with a rare heterozygous complement regulatory factor (CFI) I gene mutation (case report)
This case report presented an association between a rare heterozygous CFI mutation and neurological manifestations with more than 15 episodes of aseptic neutrophilic meningitis, seizures, and persistent cognitive impairments.
Autologous hematopoietic stem cell transplantation in 32 patients with aggressive relapsing-remitting multiple sclerosis
This study reports the results of autologous hematopoietic stem cell transplantation in 32 patients with relapsing-remitting multiple sclerosis.
Autoreactive T-cells migrate into the bone marrow and augment myelopoiesis which can accelerate inflammation and demyelination in MS
This study revealed that bone marrow, as the primary site of hematopoiesis, has an unrecognized role in MS, promoting intimate interactions between autoreactive T-cells and hematopoietic cells.
Plasma and tear fluid concentrations of calcitonin gene-related peptide are related to the endogenous sex hormone levels during the menstrual cycle phases in women suffering from episodic migraine
The increased CGRP release from the trigeminal-vascular system during menstruation could explain the biological predisposition to more frequent, severe, and prolonged migraine attacks during this period
Sex-specific differences in functional brain connectivity are present in utero
Sex-specific differences in brain functional connectivity are present in utero in a way that is consistent and reliable enough to be highly identifiable.
College athletes who had a slow recovery from a sports-related brain concussion were more likely to be female and had a greater number of symptoms immediately after injury
Women have a delayed resolution of sports-related post-concussive symptoms compared to men, and a greater number of neurological and behavioral symptoms, such as increased reaction times and more difficulties with visual memory tasks.
The relationship between the volumes and microstructural properties of callosal subregions and the degree of language lateralization in the corresponding cortical areas
This first tractography study investigated the relationship between the volumes and microstructural properties of callosal subregions and the degree of language lateralization.