The Department of Health and National Notifiable Diseases Surveillance System of the Australian Government reported a rise in the prevalence of cryptosporidiosis in Australia.
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A rise of toxic shock syndrome in Japan
The Japanese National Institute of Infectious Diseases reports a rise in the number of patients with toxic shock syndrome in Japan.
Anthrax outbreak in Zambia (The WHO announcement)
On December 8th, 2023, the World Health Organization announced that Zambia had reported its largest anthrax outbreak for a decade.
Other Entries
The accumulation of nanoparticles in the reproductive organs of female mice
The accumulation of nanoparticles in the female reproductive organs impairs the development of oocytes and can compromise fertility. In addition, cancer treatment with nanomedicines appears to be influenced by the specific biodistribution of nanoparticles in the female reproductive system.
Systemic inflammation induced by lipopolysaccharide reduced the number of hippocampal GABA-ergic synapses and caused memory impairment
A short time after systemic inflammation induced by lipopolysaccharide, microglia were activated, followed by a reduced number of hippocampal γ-aminobutyric acid (GABA)-ergic synapses and long-lasting cognitive impairment.
Certain bacterial species in colorectal cancer can resist the toxicity of 5-fluorouracil and reduce drug efficacy
In some patients with colorectal cancer, the intratumoral microbiota possesses the ability to deplete 5-FU, thereby reducing the efficacy of chemotherapeutic agent within the colonized microniches.
Bat coronavirus TyRo-CoV-162275, found in southern China, has a furin protease cleavage site in the spike protein
Bat coronavirus TyRo-CoV-162275 has a putative furin protease cleavage site in its spike protein, and similar to MERS-CoV, likely utilizes human dipeptidyl peptidase-4 (hDPP4) as a receptor for cell entry.
The American Heart Association recently defined the cardiovascular-kidney-metabolic syndrome
AHA presidental advisory provides the definition of cardiovascular-kidney-metabolic syndrome syndrome and guides how to better detect, prevent, and manage it.
A possible role of tau protein dysregulation in the pathogenesis of glaucoma
This review article discusses the new perspective of glaucoma as a tau-associated disorder, and analyzes the recent findings on the link between tau protein dysregulation and glaucomatous neurodegeneration.
The risk of cardiac arrhythmias is increased in patients with inflammatory bowel disease (nationwide Swedish cohort study)
The patients with inflammatory bowel disease had an increased long-term risk of developing cardiac arrhythmias, with the exception of bradyarrhythmias
Concurrent infection with different intracellular pathogens can lead to accelerated T-cell exhaustion and potentially severe consequences
This paper discusses the possible interactions between the first and the second intracellular pathogens, such as viruses, bacteria, fungi and protozoan parasites, when they concurrently infect the same host cells.
The gender-specific association between depressive symptoms and specific forms of childhood trauma in patients with recent-onset schizophrenia spectrum disorders
This study revealed a gender-specific association between depressive symptoms and specific forms of childhood trauma in patients with recent-onset schizophrenia spectrum disorders. In women, the severity of depressive symptoms was associated with childhood sexual abuse, which was three times as often as in men.
AEF0117, a signaling-specific inhibitor of the type 1 cannabinoid receptor, is a safe and potentially effective treatment for cannabis use disorder
This study showed that AEF0117 reduced the positive subjective effects of cannabis and self-administration of cannabis in individuals with cannabis use disorder in comparison to placebo. It seems that AEF0117 decreases the abuse-related effects of cannabis not affecting normal behavior or activities.
Treatment with ADHD medications is associated with reduced risk of suicide in patients with borderline personality disorder (a nationwide Swedish study)
The use of ADHD medications was associated with a reduced risk of attempted or completed suicide. On the contrary, the use of benzodiazepines was associated with a marked increase in suicide risk.
Gender-specific differences in proteomics in patients with heart failure and reduced ejection fraction
Women and men with heart failure with a reduced ejection fraction had different baseline levels of circulating cardiovascular proteins. In addition, the predictive value of repeatedly measured circulating proteins did not differ, except for endothelin-1 and somatostatin.
The neurogenic cardiac injury
This review discusses the main pathophysiological mechanisms of heart-brain interaction leading to the neurogenic cardiac injury.
A vascular graft from a combination of tropoelastin and polyglycerol sebacate mimics the structure of living blood vessels
Researchers developed a a novel vascular graft from a combination of tropoelastin (TE) and polyglycerol sebacate (PGS) that mimics the structure of living blood vessels.
The third case of HIV-1 cure after allogeneic CCR5Δ32/Δ32 hematopoietic stem cell transplantation
This study reports the third case of HIV-1 cure after allogeneic CCR5Δ32/Δ32 hematopoietic stem cell transplantation, and provides detailed information about the virological and immunological signature before and after analytical treatment interruption.
