The avian influenza A (H5N1)

The attachment pattern, replication, and infection of the upper and lower human respiratory tract differ between the H5N1 virus of clade 2.3.4.4b, the H5N1 virus of clade 2.1.3.2 and a seasonal H3N2 virus

Dec 5, 2024

Currently circulating the HPAI H5N1 virus of clade 2.3.4.4b attached better to the human respiratory tract than the H5N1 virus of clade 2.1.3.2. More abundant attachment to the human respiratory tract of the H5N12022 virus was associated with its more effective replication.

The risk of transmission of influenza A H5N1 virus through direct contact with raw milk from infected dairy cows (the mammary gland of cows abundantly displays receptors for circulating 2.3.4.4b H5 viruses)

Nov 17, 2024

Recent studies have investigated the ongoing risk of transmission of highly pathogenic avian influenza (HPAI) A(H5N1) virus to humans through direct contact with raw milk from infected dairy cows, the binding of 2.3.4.4b H5 influenza A viruses to available receptors in the mammary gland tissue samples from cows.

A teenager who was hospitalized in British Columbia and tested positive for Influenza A (H5N1), clade 2.3.4.4b, genotype D1.1, is the first case of avian influenza in Canada

Nov 16, 2024

On November 13, 2024, the Public Health Agency of Canada confirmed the first domestically acquired human case of avian influenza (also known as bird flu) caused by the influenza A(H5N1) virus in Canada.

Other Entries

14% of Texas dairy farmworkers tested had elevated levels of neutralizing antibodies against a recombinant Influenza A(H5N1) virus of clade 2.3.4.4b

Oct 20, 2024

Experts are warning that human cases of the H5N1 avian flu could be going undetected due to poor surveillance and a lack of diagnostic testing in at-risk groups.