Topic

Long COVID/ Post-COVID-vaccination syndrome & Cardiovascular system

Recurrent venous thromboembolism in patients who discontinued anticoagulant therapy for COVID-19-associated venous thromboembolism after at least three months of treatment

After discontinuation of anticoagulation therapy, recurrent VTE occurred in 3.5% of patients, with a rate of 3.1 per 100 patient-years, and no fatal pulmonary embolism.

Orthostatic intolerance, a cardiovascular autonomic disorder, and decreased circulating growth hormone levels have been found in young patients with long COVID syndrome

This study showed a high rate (38%) of standing test positivity in patients with long COVID. The ST-positive long COVID patients under 20 years of age had decreased circulating growth hormone levels.

The SARS-CoV-2 spike protein acts as an allosteric agonist of β-adrenergic receptors and contributes to sympathetic hyperactivity

This study is the first to show that the SARS-CoV-2 spike protein activates β-adrenergic receptors in cardiomyocytes, contributes to cardiac sympathetic hyperactivity and increases activation of downstream β-adrenergic receptor signaling induced by epinephrine.

Spontaneous dissection of the internal carotid artery in a fully vaccinated woman infected with SARS-CoV-2 (case report)

This case report describes a fully vaccinated woman positive for a non-Omicron variant of SARS-CoV-2 who experienced a spontaneous internal carotid dissection. A dissection was treated successfully with a flow-diverter stent.

Extensive thrombosis of cerebral venous sinuses and similar organization of cerebral thrombi were found in all three patients who died of vaccine-induced immune thrombotic thrombocytopenia

The authors performed the immunohistological analysis of clots from three people who died from cerebral venous thrombosis (CVT) related to vaccine-induced immune thrombotic thrombocytopenia (VITT) after receiving a single dose of ChAdOX1-nCoV-19, AstraZeneca/Oxford vaccines.

The mRNA COVID-19 vaccination increases the risk of retinal vascular occlusion

The overall risk of all forms of retinal vascular occlusion was 2.19 times higher in the vaccinated cohort than in the unvaccinated cohort within two years after COVID-19 vaccination.