The results showed that the perimenopause (2 years prior and 2 years after the final menstrual period) is a period of increased risk of first-onset major depressive disorder and mania.
Category
Sex-related differences in human medicine
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Differences in gene transcriptomics in peripheral blood cells of vaccinated patients with post-COVID syndrome are sex-specific
Sex-specific differences in the transcriptome of peripheral blood cells in vaccinated patients with PACS indicate possible sex-specific differences in the pathophysiology of PACS.
A Korean nationwide study conducted on more than 44 million vaccinated individuals found that the incidence of myocarditis associated with COVID vaccination was highest in males aged 12 to 17 years, and the most serious adverse effect was sudden cardiac death
The authors concluded that the findings of sudden cardiac deaths attributable to COVID vaccine-related myocarditis warrant the careful monitoring or warning of sudden cardiac death as a potentially fatal complication of COVID-19 vaccination, especially in individuals younger than 45 years of age who received the mRNA vaccines.
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Sex-specific proteomic profiles of patients with heart failure and reduced ejection fraction
Circulating proteins associated with extracellular matrix organization were overrepresented in women, while those reflecting apoptotic processes were overrepresented in men. The predictive value of circulating proteins measured repeatedly did not differ between sexes, except for endothelin-1 and somatostatin.
Neuroplasticity of the maternal brain during pregnancy and postpartum
The specific changes in physiology and neuroplasticity in the maternal brain during pregnancy prepare the mother for the challenges of motherhood and contribute to the survival of the offspring.
Hypotestosteronemia in COVID-19 or post COVID syndrome could be of hypothalamic origin
A persistent hypotestosteronemia in certain patients with COVID-19 or long COVID syndrome could be of hypothalamic origin due to impaired GnRH function, or hypogonadotropic hypogonadism.
HERV expression in pregnant women with multiple sclerosis is reduced compared to healthy pregnant women
The expression of HERVs in pregnant women with MS was reduced compared to healthy pregnant women.
The VAERS reporting rates of myocarditis/pericarditis after mRNA COVID-19 vaccination demonstrate a higher reporting rate mainly after the second dose, particularly among young males
In this retrospective pharmacovigilance study of safety signals associated with myocarditis/pericarditis after the primary and up to three booster doses of mRNA COVID-19 vaccines, the second dose of the vaccines showed the strongest signal in vaccinated individuals under 25 years old.
Sex-specific association between depressive symptoms and specific forms of childhood trauma in patients with recent-onset schizophrenia spectrum disorders
This study revealed a gender-specific association between depressive symptoms and specific forms of childhood trauma in patients with recent-onset schizophrenia spectrum disorders. In women, the severity of depressive symptoms was associated with childhood sexual abuse, which was three times as often as in men.
Sex-specific association between ultra-processed foods and the increased risk of colorectal cancer
This study found a positive association between the overall consumption of ultra-processed foods and the increased risk of colorectal cancer in men. The association was limited to distal colon cancer.
Plasma and tear fluid concentrations of calcitonin gene-related peptide are related to the endogenous sex hormone levels during the menstrual cycle phases in women suffering from episodic migraine
The increased CGRP release from the trigeminal-vascular system during menstruation could explain the biological predisposition to more frequent, severe, and prolonged migraine attacks during this period
Sex-specific differences in functional brain connectivity are present in utero
Sex-specific differences in brain functional connectivity are present in utero in a way that is consistent and reliable enough to be highly identifiable.
Female college athletes are more likely to have a longer recovery after a sport-related brain concussion
Participants who experienced slow recovery after sport-related brain concussion were more likely to be women and have more symptoms immediately after injury.
