These findings suggest that the persistence of vaccine-derived S1 protein in CD16+ monocytes, and post-acute sequelae of COVID-19-like cytokine profile, may contribute to persistent post-COVID-19 vaccination syndrome.
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One year after mRNA COVID-19 immunization, the young people show elevated cytokine levels, suggesting ongoing stimulation of the immune system
The results showed that vaccination led to increased cytokine levels even one year after vaccination. Furthermore, the results indicated differences in cytokine levels based on gender and age.
SARS-CoV-2 infection in vitro triggered the inflammation and senescence pathways in A9 dopaminergic neurons (mostly affected by Parkinson’s disease in the substantia nigra) derived from human pluripotent stem cells. Increased risk of viral-induced parkinsonism?
This study demonstrated selective in vitro vulnerability of A9 DA neurons derived from human pluripotent stem cells to SARS-CoV-2 infection and the associated inflammatory and cellular senescence response.Â
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SARS-CoV-2 can infect and replicate in human motor neurons differentiated from induced pluripotent stem cells
SARS-CoV-2 is able to infect and replicate in an in vitro model of human motor neurons differentiated from induced pluripotent stem cells.
Acyclovir clinically resolved or significantly improved symptoms in patients diagnosed with long COVID syndrome
Two case series studies demonstrated that four patients with long COVID improved with chronic use of acyclovir.
The neurogenic cardiac injury
This review discusses the main pathophysiological mechanisms of heart-brain interaction leading to the neurogenic cardiac injury.
