Comparative genomic analysis of a collection of 339 S. aureus isolates from patients with bacteremia highlighted bacterial adaptation to COVID-19 selective pressure.
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The rapid waning of serum antibodies after mRNA vaccination is due to the inability of mRNA vaccines to induce long-lived plasma cells in the bone marrow
This study showed the exclusion of SARS-CoV-2 specificity from the bone marrow long-lived plasma cell (LLPC) compartment and the inability of mRNA vaccines to induce necessary precursor programs to fully mature into the bone marrow LLPC.
Histamine receptor H1 acts as an independent receptor for SARS-CoV-2
Histamine receptor H1 acts as an independent receptor for SARS-CoV-2. Additionally, H1 directly interacts with ACE2, synergistically enhancing ACE2-dependent viral entry.
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IgG4-related diseases (sialadenitis, pancreatitis, and hepatopathy) after COVID-19 vaccination
The authors from Japan presented two cases of immunoglobulin (Ig)G4-related diseases that developed after anti-SARS-CoV-2 vaccination.
SARS-CoV-2 can infect and replicate in human motor neurons differentiated from induced pluripotent stem cells
SARS-CoV-2 is able to infect and replicate in an in vitro model of human motor neurons differentiated from induced pluripotent stem cells.
Acyclovir clinically resolved or significantly improved symptoms in patients diagnosed with long COVID syndrome
Two case series studies demonstrated that four patients with long COVID improved with chronic use of acyclovir.
Acute disseminated encephalomyelitis (ADEM) can develop after acute SARS-CoV-2 infection or COVID-19 vaccination
A systematic review of the medical literature on cases of acute disseminated encephalomyelitis (ADEM) and acute hemorrhagic leukoencephalitis (AHLE) that occurred after severe acute SARS-CoV-2 infection or CoVID-19 vaccination.
The neurogenic cardiac injury
This review discusses the main pathophysiological mechanisms of heart-brain interaction leading to the neurogenic cardiac injury.