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The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can infect the human placenta. In this study, the authors from Italy performed immunohistochemical analyses to determine whether SARS-CoV-2 alters markers involved in vascular damage and the autophagic...
These results demonstrated that nAChR subtypes interact with the neurotoxin-like region of the SARS-CoV-2, confirming that the α7 nAChR is a target for the SARS-CoV-2.
This study found, for the first time in children, that levels of IgG4 antibodies specific for S1 and RBD significantly increased one year after the second vaccination compared to baseline.
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Seven antigenic sites of SARS-CoV-2 spike RBD showed molecular similarities with 54 antigenic determinants found in fifteen pathogen microorganisms, including bacteria, parasites and viruses.
Different beta-coronaviruses (β-CoVs) contain prion-like domains in the S proteins. However, SARS-CoV-2 is the only β-CoV with prion-like domains identified within the receptor-binding domain (RBD) of the S protein.
The authors from Japan presented two cases of immunoglobulin (Ig)G4-related diseases that developed after anti-SARS-CoV-2 vaccination.
Two case series studies demonstrated that four patients with long COVID improved with chronic use of acyclovir.
IL-6 receptor blocker tocilizumab rapidly improved the condition in two children with severe, acute manifestations of myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD).
